Antineutrophil cytoplasmic antibody mediated glomerulonephritis associated with levamisole-adulterated cocaine
نویسندگان
چکیده
منابع مشابه
Antineutrophil cytoplasmic antibody mediated glomerulonephritis associated with levamisole-adulterated cocaine
Levamisole-adulterated cocaine has increased in prevalence over the last decade and is known to be associated with antineutrophil cytoplasmic antibodies (ANCA). Dermatologic manifestations of levamisole exposure, including cutaneous vasculitis, are widely appreciated; less is known about its effects on the kidney. We report two cases of patients with a history of cocaine abuse and levamisole-in...
متن کاملPurpura, cutaneous necrosis, and antineutrophil cytoplasmic antibodies associated with levamisole-adulterated cocaine.
OBJECTIVE To describe the clinical and serologic abnormalities in 6 patients who presented with retiform purpura and extensive cutaneous necrosis after exposure to levamisole-adulterated cocaine. METHODS All patients were evaluated at San Francisco General Hospital or the University of California San Francisco Medical Center. Each underwent standard screening for substances of abuse and had u...
متن کاملCutaneous vasculopathy associated with levamisole-adulterated cocaine.
We report a case of cutaneous vasculopathy associated with the use of levamisole-adulterated cocaine. This recently described clinical entity is characterized by a purpuric rash with a predilection for the ears, leukopenia, and anti-neutrophilic cytoplasmic antibody (ANCA) positivity. It is estimated that more than 70% of the current United States cocaine supply is contaminated with levamisole....
متن کاملPauci-Immune Glomerulonephritis in Individuals With Disease Associated With Levamisole-Adulterated Cocaine
Exposure to levamisole-adulterated cocaine can induce a distinct clinical syndrome characterized by retiform purpura and/or agranulocytosis accompanied by an unusual constellation of serologic abnormalities including antiphospholipid antibodies, lupus anticoagulants, and very high titers of antineutrophil cytoplasmic antibodies. Two recent case reports suggest that levamisole-adulterated cocain...
متن کاملAgranulocytosis from levamisole-adulterated cocaine.
INTRODUCTION Afebrile neutropenia with an absolute neutrophil count (ANC) of zero in a nonimmunocompromised individual is unusual. Outlined is a case of agranulocytosis likely due to levamisole laced cocaine. Given recent publications in the news media and medical journals, this is a pertinent issue for primary care providers. CASE A 57-year-old female presented with painful bowel movements a...
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ژورنال
عنوان ژورنال: Clinical Nephrology – Case Studies
سال: 2014
ISSN: 2196-5293
DOI: 10.5414/cncs108385